Clinical Resources
PONS Presentation: Management of Super Refractory Status Epilepticus (No CEU)
,
Super refractory status epilepticus (SRSE) is a neurologic emergency that requires prompt recognition and aggressive
treatment. Although guidelines recommend early initiation of continuous intravenous (cIV) anesthetics, the optimal
dosing, monitoring, titration and weaning strategy for these agents is unknown. Moreover, a preferred algorithm
including when to add concomitant antiepileptics (AEDs) versus when to initiate cIV anesthetics is controversial due to
the lack of high quality clinical evidence. This presentation reviews the available cIV medications used for RSE and
helps clinicians develop an algorithm for the treatment of RSE that can be individualized for complex patients.
Following the presentation, clinicians should be aware of the emergent nature of RSE as well as treatment options,
appropriate monitoring, and approach to clinical controversies.
Presentation Objectives:
- Compare and contrast the continuous infusions for refractory status epilepticus (RSE)
- Review nonpharmacologic and novel treatment options for super RSE (SRSE)
- Develop an algorithm for the treatment of SRSE and apply it to complex patients